complications of dengue fever ppt
2008 Nov. 79(5):673-7. N Engl J Med. BMC Infect Dis. Among the numerous target cells for dengue virus in humans are monocytes, macrophages and mast cells which are important regulators of vascular integrity and which undergo dramatic cellular responses after infection by dengue virus. [Medline]. [Medline]. A rapid deterioration can occur 2-5 days after onset of fever. Cities spawn epidemic dengue viruses. However, although these severe complications are infrequent and are usually readily identifiable, the spectrum of clinical manifestations is broad and can be quite subtle. Gubler DJ. Michael Stuart Bronze, MD is a member of the following medical societies: Alpha Omega Alpha, American College of Physicians, American Medical Association, Association of Professors of Medicine, Infectious Diseases Society of America, Oklahoma State Medical Association, Southern Society for Clinical InvestigationDisclosure: Nothing to disclose. 2010 Oct. 83(4):774-80. The magnitude of prolonged APTT and PT among patients with dengue fever infection were 42.91% (95% CI: 30.95, 54.87) I2 = 99.1% and 16.48% (95% CI: 10.95, 22.01) I2 = 97.0%, respectively. It cannot be spread from one person to another. fatal complications. A vast majority of cases are asymptomatic or mild and self-managed, and hence the actual numbers of dengue cases are under-reported. 12th Annual Conference on Vaccine Research. The leading dengue vaccine candidate, ChimeriVax (Sanofi Pasteur), is a tetravalent formulation of attenuated yellow fever 17D vaccine strains expressing the dengue virus prM and E proteins. The symptoms of painful eye with eye discharge and swelling may herald more serious eye complications, and an urgent specialist review by ophthalmologist should be sought. Pediatr Infect Dis J. 7 Risk factors associated with severe disease of dengue … Bhatt S, Gething PW, Brady OJ, Messina JP, Farlow AW, Moyes CL, et al. Complications of Dengue Fever About 1 in 20 people with dengue will develop severe dengue, according to the CDC. Disease Prognosis Dengue Self-limiting disease; mortality rate of < 1% fever/ (dengue fever) when treated, dengue Dengue Hemorrhagic fever mortality rate of 2- Hemorrhag ic fever 5% Untreated, mortality rate can be as high as 50% FACTORS THAT AFFECT DISEASE SEVERITY: • Age • Nutritional status … Many cases are also misdiagnosed as other PLoS Negl Trop Dis. If a dengue fever gets worse, it can lead to dengue hemorrhagic fever dengue shock syndrome. –Misdiagnosis in regions where dengue and other infectious diseases with overlapping presentations ... •Most complications are associated with localisation of leptospires within the tissue during the immune ... of fever, improved renal function quicker and shorten Lancet Infect Dis. [Medline]. People with malaria often experience fever, chills, and flu-like illness. Travel-associated Dengue surveillance - United States, 2006-2008. Accessed: January 25, 2014. Rothman AL, Ennis FA. Dengue optic neuropathy. Fatal hemophagocytic lymphohistiocytosis associated with locally acquired dengue virus infection - new Mexico and Texas, 2012. [Medline]. 14(1):121-40, ix. Dengue infections during pregnancy: a case series from Sri Lanka and review of the literature. 2(9):e300. Accessed: October 20, 2011. Bottieau E, Clerinx J, Van den Enden E, Van Esbroeck M, Colebunders R, Van Gompel A. [Medline]. Wilder-Smith A, Gubler DJ. [Medline]. Dengue fever is common in tropical areas, so take extra precautions if you travel somewhere with this type of climate. Dengue: update on epidemiology. Increasing rates of dengue infection by regions of the world. Dengue: defining protective versus pathologic immunity. 2005 Apr. [Medline]. xxx00.#####.ppt 12/16/2019 11:53:12 AM Pediatrics Dengue Virus •Flavivirus •Four serotypes ‐DEN-1, DEN-2, DEN-3, DEN-4 •Lifelong immunity •Complicated illness with secondary infection of different serotype •Three classifications of disease ‐Dengue Fever (DF) ‐Dengue Hemorrhagic Fever (DHF) ‐Dengue Shock Syndrome (DSS) Available at http://www.who.int/topics/dengue/en/. [Full Text]. Introduction For Pakistan, dengue has been established as a public health problem. Suaya JA, Shepard DS, Siqueira JB, et al. Guzman MG, Alvarez M, Rodriguez-Roche R, Bernardo L, Montes T, Vazquez S. Neutralizing antibodies after infection with dengue 1 virus. 2008 Dec. 51(6):812-3. [Medline]. Several studies reported lack of correlation between the categories of the conventional classification and the disease severity. Severe dengue . Worldwide distribution of dengue in 2003. Using any information provided by the website is solely at the viewers’ discretion. [Medline]. 2008 Nov. 92(6):1377-90, x. The etiologic agent and vector of dengue: History of dengue in the United States. Bull World Health Organ. Teves Maria A. [Full Text]. Shepard DS, Coudeville L, Halasa YA, Zambrano B, Dayan GH. [Full Text]. Severe and potentially fatal. A viral disease primarily spread through bites from infected . Aedes albopictus. Locally acquired Dengue--Key West, Florida, 2009-2010. Chowell G, Torre CA, Munayco-Escate C, Suárez-Ognio L, López-Cruz R, Hyman JM. Dengue fever occurs in tropical and subtropical areas of the world. [Medline]. [Medline]. Dengue haemorrhagic fever: diagnosis, treatment, prevention and control. Insects. 354(2):119-30. 49(12):248-53. Imported dengue--United States, 1997 and 1998. [Medline]. [Medline]. 2006 Oct. 19(5):429-36. Edelman R. Dengue vaccines approach the finish line. Dengue is an acute febrile illness that is characterized by symptoms that include fever, headache, myalgia, retro-orbital and joint pain, and rash. Do not take aspirin and other NSAIDS until dengue fever can be ruled out Supportive treatment for complications Zika in the U.S. (as of April 20, 2016) Note: Zika virus disease and Zika virus congenital infection are nationally notifiable conditions. Have you ever noticed, what causes dengue? Schmidt AC. 2007 Jan. 86(1):18-25. Med J Malaysia. Dengue fever was first referred as “water poison” associated with flying insects in a Chinese medical encyclopedia in 992 from the Jin Dynasty (265-420 AD). Ten threats to global health in 2019. [Medline]. … 83(4):308-14. Occasionally petechia are present. Emerg Infect Dis. damage to blood vessels. European Medicines Agency. Dengue Fever: An acute febrile illness of 2-7 days duration with two or more of the following manifestations: Headache, retro-orbital pain, myalgia, arthralgia, rash, hemorrhagic manifestations. Found insideThe Third Edition features 1,500 full-color illustrations (800 more than the second edition), an even more effective template, and new coverage of airway emergencies, tropical conditions, toxicologic emergencies, and electrocardiographs. Immunopathogenesis of Dengue hemorrhagic fever. A successful management of dengue fever in pregnancy: report of two cases. Many of the studies included in these guidelines are based upon the management of dengue in children. Premaratne R, Pathmeswaran A, Amarasekara ND, et al. 356(3):763-8. ¾It appears to be an immunopathological consequence of the infection of a person with a virus of one serotype who has developed immunity to another serotype, although the mechanism is … The purpose of this manual is to provide a resource for training to increase understanding of Health in All Policies (HiAP) by health and other professionals. The following are the first signs and symptoms: It's good if you notice the first signs and symptoms, but if gone unnoticed, then the dengue fever can cause severe complications in various forms of itself. 2006 Sep. 37(1):27-33. 2007 Nov 10. Medical complications due to dengue can include pleural and cardiac effusion, hemorrhage, shock, or death, and dengue has a case-fatality rate that ranges from 0.5 to 5 … 2000 Mar. CDC. Article CAS PubMed Google Scholar Dengue vaccine: WHO position paper â July 2016. If you have any of the symptoms of severe dengue, you should seek immediate medical help to prevent the disease progression. [Medline]. Successful establishment of Wolbachia in Aedes populations to suppress dengue transmission. Although most cases are asymptomatic, severe illness and death may occur. Moreover, a febrile convulsion (a seizure which happens when the normal brain activity is disturbed by a fever) is another complication in it. Southeast Asian J Trop Med Public Health. Reinfestation by Aedes aegypti in the Americas after the 1970 (left) mosquito eradication program and most recent distribution as of 2002 (right). The global distribution and burden of dengue. [Medline]. 365(9459):613-7. Found insideThis edited book Dengue - Immunopathology and Control Strategies contains eight chapters divided in three sections that underline important aspects of dengue virus, the most prevalent and life-threatening arbovirus in the world, including ... Dengue fever is contracted from the bite of a striped Aedes aegypti mosquito. Epidemiol Infect. [Full Text]. A complex interplay among virus, dendritic cells, T cells, and cytokines in dengue virus infections. Later, there may bebleeding tendency: such as skin bruises, nose or gum … Effect of dengue-1 antibodies on American dengue-2 viral infection and dengue haemorrhagic fever. Found insideThis handbook is an updated edition of 'Management of severe and complicated malaria', providing practical guidance on the diagnosis and management of severe falciparum malaria, a form of the disease that can have life-threatening ... [Medline]. In Venezuela we are known to have all the serotypes (Den-1, Den-2, Den-3 and Den-4) constantly cycling and maintaining a dengue fever to dengue hemorrhagic fever ratio of 10:1, with a mortality rate of 0,63%. J Clin Virol. Courtesy of the Centers for Disease Control and Prevention (CDC). Male-female differences in the number of reported incident dengue fever cases in six Asian countries. 2004 Oct. 80(948):588-601. This manual provides expert practical guidelines for the management of severely malnourished children. This publication is intended to contribute to prevention and control of the morbidity and mortality associated with dengue and to serve as an authoritative reference source for health workers and researchers. 2003 Mar. Malavige GN, Fernando S, Fernando DJ, Seneviratne SL. Setiati TE, Mairuhu AT, Koraka P, Supriatna M, Mac Gillavry MR, Brandjes DP, et al. Domingo C, de Ory F, Sanz JC, Reyes N, Gascón J, Wichmann O, et al. Liver involvement associated with dengue infection in adults in Vietnam. This website uses cookie or similar technologies, to enhance your browsing experience and provide personalised recommendations. fatal complications. Lassa fever is a viral disease spread by the the multimammate rat. Gã¶âÜT{/fè3[n«~d³[>®¾³)ÜUù|ÖK!YÞÙ}Á[¦¶\njõª«¬5HíAIÜÒýùWýôêÂGùÕÄõÖê¼GÝpn£«ª)©#þ+OM3SUµBLoY. Lancet 360 , 310–312 (2002). Comprehensive Guidelines for Prevention and Control of Dengue and Dengue Haemorrhagic Fever vii Dengue fever is the fastest emerging arboviral infection spread by Aedes mosquitoes with major public health consequences in over 100 tropical and sub-tropical countries in South-East Asia, the Western Pacific and South and Central America. [Medline]. [Full Text]. Dengue and yellow fever--challenges for the development and use of vaccines. Blaney JE Jr, Durbin AP, Murphy BR, Whitehead SS. [Medline]. Sharp TM, Gaul L, Muehlenbachs A, Hunsperger E, Bhatnagar J, Lueptow R, et al. It includes: Do you know that chronic dengue could lead to DSS or DHF? Aguiar M, Stollenwerk N, Halstead SB. Dengue (pronounced DENgee) fever is a painful, debilitating mosquito-borne disease caused by any one of four closely related dengue viruses. 5 (4):991-1000. [Medline]. Ophthalmology. 2004 Feb. 10(2):129-30. 257(1):1-6. [Full Text]. [Medline]. Chen LC, Lei HY, Liu CC, Shiesh SC, Chen SH, Liu HS. 496 (7446):504-7. [Medline]. 1993 Jul. WHO. The symptoms of dengue range from mild fever to even fatal condition. Replication of dengue virus type 2 in human monocyte-derived macrophages: comparisons of isolates and … By mosquitoes use as bedside diagnosis of dengue fever fever dengue shock syndrome is severe, swollen. 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