chikungunya transmission

You can also make a donation by PayPal and support the Chikungunya Virus Net website. Unable to load your collection due to an error, Unable to load your delegates due to an error. As newborns infected in the peripartum period are born with very low or even undetectable viremia, placental microtransfusion seems unlikely as expected neonatal viremia would be close to that of the mother. A serological study of 80. here. PLoS Negl. 2017 Jan 20;11(1):e0005319. Although they are most active during daylight hours, biting from dawn to dusk, mosquitoes will feed throughout the day indoors and during overcast weather. Writing – original draft, 3. International Journal of Scientific and Research Publications, Volume 10, Issue 2, February 2020 750. Infected humans are the main carriers and multipliers of the virus, and serving as a source of the virus for uninfected mosquitoes. PLoS Negl Trop Dis. It means 'to become contorted', as the disease . All studies included newborn infants hospitalized in neonatal intensive care units (NICUs), with clinical chikungunya and laboratory evidence of viral infection. Chikungunya is a virus that's spread by mosquitoes.It can't be passed from person to person. Found inside – Page 327[Early maternal-fetal transmission of the Chikungunya virus]. Presse Med 2006;35(11 Pt 1):1656–8. 50. Lenglet Y, Barau G, Robillard PY, et al. 7) of their total area identified as persistent disease hotspots. There is no way to tell if a mosquito is carrying the chikungunya virus. The median length of hospital stay was 18 days (3–69 days). We included studies with clinical and laboratory neonatal data, as well as age in days at onset of illness and outcome in the neonate such as sequelae or death. You can also download the original image in high resolution as jpg, tiff or powerpoint file. Found inside – Page 1126Chikungunya virus is transmitted from one human to another primarily by infected Aedes aegypti and Aedes albopictus mosquitoes. Enzootic transmission cycles ... Chikungunya virus (CHIKV) is an arthropod-borne virus (arbovirus) of the alphavirus genus (Togaviridae family) that is believed to have originated in Africa, where it was known to circulate in sylvatic and urban cycles involving female mosquito vectors of the genus Aedes and non-human or human primates [1,2]. A case series study during an epidemic in Sri Lanka reported 50 pregnant women with serological proof of CHIKV infection, and among these one single case of first trimester miscarriage and one stillbirth at 33 weeks [51]. Data curation, Validation, As it is the case in pregnant women, there is no specific treatment for chikungunya in the neonate. She developed preeclampsia with severe respiratory failure which resulted in the emergency cesarean section, and the patient died 12 days after the onset of symptoms [25]. Other symptoms include muscle pain, headache, nausea, fatigue and rash. The most common symptoms of infection are fever and joint pain. In twelve studies (28.5%), the timing of onset of symptoms before childbirth was not reported. No, Is the Subject Area "Reverse transcriptase-polymerase chain reaction" applicable to this article? Saint Pierre is responsible for 40% of the total births on the island, but the epidemic also affected the eastern region and we do not have these data. Whether the vertical transmission occurs through the syncytiotrophoblast or per mucosa during childbirth remains undiscovered. https://doi.org/10.1371/journal.pone.0249166.g001. The approach of this systematic review differs from the recent meta-analysis, published in 2018, as the latter is a study of an epidemiological nature while this review is aimed at the medical public and provides additional information for obstetricians and neonatologists complementing the meta-analysis information. In the other one, a 28-year-old pregnant woman with hypertension presented with symptoms compatible with an arboviral disease at 34 weeks’ gestation. En zones urbaines, où sont décrites la majorité des épidémies, la transmission se fait d'homme à homme par l'intermédiaire de moustiques du genre Aedes notamment (Aedes albopictus et . Similarly the predicted temperatures are better suited for Aedes vectors development and diseases transmission. "Chikungunya virus can cause debilitating joint pain that can last for months or even longer," said NIAID Director Anthony S. Fauci, M.D. e0249166. 10.1056/NEJMra1406035 Infections were independently and positively associated with residences served by unpaved streets, a presumptive clinical diagnosis of chikungunya, and recall of an episode of fever with arthralgia in 2015-2016. The quantitative analysis of the study is impaired since the denominator of the number of cases on Reunion Island is unknown due to the absence of birth records from other places on the Island, with only data from the Saint Pierre region in the south of the Island. Arthralgia was little reported in the articles evaluated because pain was not assessed, therefore it is important to routinely establish neonatal pain monitoring in neonatal ICUs [58,60,61]. Neonatal sepsis was the most common CHIKV clinical presentation in the neonate; it was reported in 36 (85.7%) studies and 250 cases. Found inside – Page 180However the Chikungunya transmission pattern is expanding during 1982–2016 period mainly in Southern, Northern and Western region in comparison with ... Seroprevalence of Chikungunya virus and living conditions in Feira de Santana, Bahia-Brazil. Subsequently, the full texts potentially eligible for inclusion were read and the same inclusion and exclusion criteria were applied. Dis. Disease Chikungunya virus (CHIKV) is an enveloped, positive-sense RNA arbovirus of the genus Alphavirus (family Togaviridae). There were 205 cases recorded during that outbreak and it confirmed that mosquito-borne outbreaks by Aedes albopictus are plausible in Europe. https://doi.org/10.1371/journal.pone.0249166.g002. Visualization, Convulsion, the main neurological manifestation in these neonates, could be due to encephalitis and intracranial hemorrhage. A previous report from Reunion Island identified three fetal losses from pregnant women who presented CHIKV clinical manifestations at about two, three and four weeks respectively before the detection of fetal death on routine ultrasound examination. Chikungunya virus is a single-stranded RNA virus that belongs to the family Togaviridae, genus Alphavirus. Found insideThis book tries to update the significant epidemiological and clinical research in many aspects with a multinational perspective. La dengue, le chikungunya et le Zika sont des arboviroses qui sont transmises par un moustique : Aedes albopictus. Writing – original draft, The mosquitoes generally acquire the virus while feeding on the blood of an infected person. A strength is the clinical characterization of signs and symptoms associated with the vertical transmission of CHIKV, which is critical for improving the diagnosis of suspected cases and the appropriate therapeutic management of infected neonates. The chikungunya virus is transmitted from human to human by the bites of infected female mosquitoes. Aedes mosquitoes may acquire the virus when they feed on an individual during this period. The selected studies were published between 2006 and 2020 and conducted between 2005 and 2019 (Table 1). Save up to 80% versus print by going digital with VitalSource. No correlation of the presence or severity of maternal symptoms with neonatal outcomes was reported. These variables may operate independently or collectively to give rise to a particular pattern of infection. Outbreaks have occurred in countries in Africa, Asia, Europe, and the Indian and Pacific Oceans. The Digital and eTextbook ISBNs for Chikungunya: Epidemiology, Transmission and Therapeutics are 9781536199871, 1536199877 and the print ISBNs are 9781536199789, 1536199788. first outbreak since 1982. Our findings indicate that the chikungunya outbreak in Salvador may not have conferred sufficient herd immunity to preclude epidemics in the near future. The data were extracted by two authors (FF and AS), disagreements were resolved by consensus reached through a third author (PB). The risk of chikungunya transmission in recent years of climate is gradually increasing in India. The presentation, similar to bacterial sepsis poses a diagnostic challenge when maternal infection has not been diagnosed. JR is an independent consultant, but has no other affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict. 1- Introduction. This scenario would represent a serious public health . (2005) Transmission of hepatitis B by human However, more chikungunya-infected travelers coming into the United States increases the likelihood that local chikungunya transmission will occur." The good news is people are immune after one . Investigation, The search descriptors used for Medline were as follows: (((congenital chikungunya) AND (((newborn) OR (((infant OR neonatal))) AND (((mother-to-child OR congenital OR vertical transmission)))) AND chikungunya). From November 2016 through February 2017, we collected sociodemographic and clinical data by interview and tested serum samples for CHIKV IgG. Similarly the predicted temperatures are better suited for Aedes vectors development and diseases transmission. No, Is the Subject Area "Arthralgia" applicable to this article? Supervision, Therapeutic management of the neonates consisted of symptomatic measures in all studies, all cases being admitted to the NICU for supportive cares due to the severity of chikungunya presentation. The mother’s chikungunya diagnosis was confirmed by RT-PCR detection of the viral genome in maternal blood two weeks before diagnosis of fetal loss; viral genome in the placenta and amniotic fluid confirmed transplacental transmission of CHIKV and its persistence after fetal death. Evidence of previous but not current transmission of chikungunya virus in southern and central Vietnam: Results from a systematic review and a seroprevalence study in four locations. Studies with no documented evidence of CHIKV infection in neonates (negative RT-PCR or absence of IgM) were excluded. Seroprevalence of Chikungunya Virus in a Rural Community in Brazil. Found inside – Page 843Chikungunya as the cause of death, although for most cases co-morbidity ... The Chikungunya virus is transmitted among baboons and humans by A. furcifer. Chikungunya virus Agriculture & Biology 100%. During the dengue epidemic in Yunnan Province, China, during 2019, a concurrent outbreak of chikungunya occurred in the city of Ruili, which is located in the southwest of the province, adjacent to Myanmar. Microorganisms. 2017;11:e0005254. "A vaccine to prevent infection with this virus would be of considerable benefit to people living in the more than 60 countries where chikungunya transmission has occurred, as well as travelers to those . Resources, Chikungunya is a viral disease transmitted to humans by infected mosquitoes. Hyperalgesia, difficult to evaluate, and irritability, although common in neonatal CHIKV, were not specific and could be due to neonatal sepsis of other etiology. PMC PLoS Negl Trop Dis. Vertical transmission was first observed in June 2005 in the CHIKV epidemic that affected more than a third of the population in Reunion Island from March 2005 to July 2006 [6,7]. The name chikungunya means "that which bends up." The disease is rarely fatal, but the severe joint pain it produces can last for months. There is no specific treatment or commercially available vaccine against the disease. Authors Rosângela O . Transmission of Chikungunya Virus in an Urban Slum, Brazil Emerg Infect Dis. CHIKV seroprevalence was 11.8% (95% CI 9.8%-13.7%), and 15.3% of seropositive persons reported an episode of fever and arthralgia. For differential diagnosis of CHIKV vertical transmission with other arboviral diseases sharing similar outcomes during gestation (miscarriage, preterm birth, fetal distress), sepsis should alert neonatologists and evoke chikungunya. These . 102330/Z/13/Z/WT_/Wellcome Trust/United Kingdom, Weaver SC, Lecuit M. Chikungunya virus and the global spread of a mosquito-borne disease. Cerebral edema may increase permeability of the blood-brain barrier without virus-induced damage of the central nervous system, but a direct virus-induced encephalitis cannot be ruled out. Seroprevalence, spatial dispersion and factors associated with flavivirus and chikungunha infection in a risk area: a population-based seroprevalence study in Brazil. In this systematic review of 42 studies that included 266 fetuses or neonates infected with CHIKV by vertical transmission, neonatal infection was severe, manifesting with neurological disease hospitalized in intensive care in 76.5% of cases. Groupe Hospitalier Sud Réunion, Reunion Island, France, Roles Visualization, 2020 Jul;26(7):1364-1373. doi: 10.3201/eid2607.190846. We developed a new age-structured deterministic model for the transmission dynamics of chikungunya virus. Fetal distress was reported in 25% of infected babies and was the cause of a cesarean delivery indication, reported in 69.2% of cases in one study [6]. Mode of Transmission of Chikungunya Virus: Humans are infected by Aedes aegypti and albopictus mosquitoes, containing Chikungunya virus when they bite (blood meal) humans. The complete search strategies were adapted according to each data base. Visualization, FOIA The gestational age of chikungunya infection in the pregnant woman was not described in 20 (47.6%) of the studies. Project administration, Azar SR, Campos RK, Bergren NA, Camargos VN, Rossi SL. Yes Chikungunya viruses are mainly transmitted to humans through the bites of infective female Aedes mosquitoes. Neonatal infection can be severe and encephalopathy or encephalitis occurs in more than half cases who require intensive care [11]. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Among these studies, there were related 18 premature deliveries/preterm births and 58 full-term deliveries/full-term neonates. CHIKV then replicates in the skin, in fibroblasts, and disseminates to the liver . 2010 Apr 27;4(4):e623, Chikungunya is most widely transmitted by the mosquitoes named Aedes aegypti (see video 1 and 2) and Aedes albopictus mosquito. The final selection resulted in 42 articles: 28 case reports, seven case series, two cross-sectional study and five cohort studies. We included studies of different design that evaluated perinatal transmission of CHIKV regarding its clinical presentation and therapeutic approach, with confirmed laboratory diagnosis in neonates (RT-PCR and/or IgM serology positive for CHIKV) and with clinical, epidemiological and/or confirmed laboratory diagnosis in pregnant women. eCollection 2017 Jan. Barreto FKA, Alencar CH, Araújo FMC, Oliveira RMAB, Cavalcante JW, Lemos DRQ, Farias LABG, Boriz ILF, Medeiros LQ, Melo MNP, Miyajima F, Siqueira AM, Freitas ARR, Cavalcanti LPG. Validation, Check here - India Today, Administration on alert as dengue, chikungunya cases rise in Nashik - Times of India, Chikungunya vaccine candidate from Bharat Biotech starts Phase 2/3 trial - BioPharma-Reporter.com, Livestock deaths prompt fear of Rift Valley fever and chikungunya outbreak in northern Sudan - Sudan - ReliefWeb, Co-Diagnostics JV CoSara Receives Clearance from Indian FDA for Chikungunya and Dengue Tests - KPVI News 6, Dengue, chikungunya cases in Maharashtra more than triple: 15 civic bodies asked to take urgent steps - The Indian Express, Co-Diagnostics JV CoSara receives CDSCO clearance for Chikungunya and dengue tests - BSI bureau, Phase II/III clinical trial of Bharat Biotech's two-dose Chikungunya vaccine candidate begins - India Today, Curaçao not sufficiently prepared for outbreak dengue, Zika and chikungunya - Curacao Chronicle. 2021 Apr 20;15(4):e0009289. Validation, In late 2013, outbreaks occurred for the first time in the Americas in the Caribbean Islands. Fetal distress was observed in 9 (21.4%) studies, of which 66,4% were deliveries by cesarean section. The transmission cycle begins when an Aedes mosquito bites someone with chikungunya when they have fever; 10 days later the virus will multiply in the salivary glands of the mosquito and will be ready to transmit the disease when the mosquito bites a healthy person, who will begin to experience symptoms 3-7 days after incubation. Most commonly, the mosquitoes involved are Aedes aegypti and Aedes albopictus, two species which can also transmit other mosquito-borne viruses, including dengue, zika and chikungunya (see figure 1). et al. This book describes the molecular biology, pathogenesis, epidemiology, and potential strategies for control of chikungunya virus (CHIKV) infection. Nicacio JM, Khouri R, da Silva AML, Barral-Netto M, Lima JAC, Ladeia AMT, do Carmo RF, Armstrong ADC. Latin American studies reported a mean gestational age of 38 and 39 weeks [33,41]. eCollection 2021 Mar. et al. Phylogenetic studies indicate that the urban transmission cycle—the transmission of a pathogen between humans and mosquitoes that exist in . Chikungunya was, from the European perspective, considered to be a travel-related tropical mosquito-borne disease prior to the first European outbreak in Northern Italy in 2007. [30, 31, 32] Other relevant laboratory findings were anemia and prothrombin time enlargement. "Today, the transmission cycle of chikungunya in Brazil takes place in urban areas and involves the A. aegypti mosquito. Serological and molecular epidemiology of the Dengue, Zika and Chikungunya viruses in a risk area in Brazil. Chikungunya transmission was reported for the first time in Europe in 2007, in an outbreak in north eastern Italy. Project administration, The disease is transmitted by the same mosquitoes involved in the dengue transmission (Aedes aegypti and Aedes albopictus); also shares some clinical signs with dengue, and . Urban Chikungunya in the Middle East and North Africa: A systematic review. 2015;372:1231–9. Notes from the field: chikungunya virus spreads in the Americas - Caribbean and South America, 2013-2014. Chikungunya virus disease (chikungunya) is a mosquito-borne infectious disease reported in at least 50 countries, mostly in the tropics. The 42 selected studies included 266 cases of vertical transmission and were conducted in countries that suffered from chikungunya epidemics, mostly Central and South America and the Caribbean, India and Reunion Island (French overseas department). One miscarriage (<22 weeks) was tested negative. From the 227 studies initially identified, 42 were selected as follows: 28 case reports, 7 case series, 2 cross-sectional studies and 5 cohort studies, for a total of 266 CHIKV infected neonates confirmed by serological and/or molecular tests. The fetal losses were not virologically analyzed in this study. MMWR Morb Mortal Wkly Rep. 2014;63:500–1. Both cell-to-cell and extracellular transmission of chikungunya virus infection was demonstrated in BHK21/C13 cell monolayers. The mode of virus infection may depend on the cell line. Keywords: Investigation, Epidemic Alphaviruses: Ecology, Emergence and Outbreaks. Hui, A.Y. Neonatologists should be aware of late manifestations and babies of symptomatic mothers should be kept in the maternity ward for a week for clinical and laboratory surveillance through serial blood count with platelet count monitoring. Advertising opportunities on Chikungunya Virus Net include standard size banners as well as text ads. Outbreaks of Chikungunya fever across the globe, spread of infection across a population and overall mutational load are the three main variables of the transmission. Departament of Neonatology, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, Brazil, Roles Conceptualization, https://doi.org/10.1371/journal.pone.0249166.t003. Seventeen studies (40.4%) reported 74 cases of thrombocytopenia (5,000–150,000 mm3) and five (11.9%) studies reported 41 cases of increased aspartate aminotransferase. From the maternal inoculum, it takes three to seven days for the CHIKV load to reach a significant level able to cause clinical disease. It is an RNA virus that belongs to the alphavirus genus of the family Togaviridae.The name "chikungunya" derives from a word in the Kimakonde language, meaning "to become contorted", and describes the stooped appearance of sufferers with joint pain (arthralgia). albopictus is established, viraemic travel-related cases may generate a local transmission of the virus as demonstrated by the sporadic events of chikungunya virus transmission since 2007. The maternal infection diagnosis was confirmed by molecular and serological tests in 31 (73.8%) studies [6,9,10,16–28,30,31,33–35,39,41,43–45,47–51,53,54] and in 243 (96.8%) women. Found inside – Page 171The chikungunya disease is an arbovirus mostly transmitted to human beings by mosquitoes species Aedes Albopictus, which was firstly identified in 1953 in ... Rarely, from mother to child. doi: 10.1371/journal.pntd.0009256. broad scope, and wide readership – a perfect fit for your research every time. The clinical and perinatal manifestations of pregnancy and the outcome of gestation were described in ten studies [9,10,16–21,23,25,27,49–51]. The first evidence of autochthonous transmission of CHIKV in Singapore was in January 2008 (Leo et al., 2009). La récente épidémie de Chikungunya dans l’Océan indien depuis 2005, a eu un retentissement jusqu’en France métropolitaine par l’observation de centaines de cas importés et par les résultats de recherches menées dans des ... Investigation, No new articles were added after searching the reference section of the selected articles (Fig 1). Comparative studies (n = 3) achieved good quality criteria, more than 60% presented adequate statistical analyses (Fig 2). It was even proposed that suckling difficulties were due to mandibular painful involvement, mimicking trismus in some cases [6]. The development of life-threatening neonatal symptoms was not associated with the severity of maternal symptoms. Thrombocytopenia (platelets <150000 mm3) was a frequent laboratory finding in the cases reported here, associated with the clinical picture of cerebral, gastrointestinal and conjunctival hemorrhages [53,58]. Together they form a unique fingerprint. Survey of the Reunion Island outbreak J Gynecol Obstet Biol Reprod (Paris) , 35 ( 2006 ) , pp. Because of differences in studies design and the small number of participants, a meta-analysis was deemed inappropriate and we focused on describing the studies in evidence with their results and a qualitative synthesis. -, Gallian P, Leparc-Goffart I, Richard P, Maire F, Flusin O, Djoudi R, et al. The R 0 predicts the optimal temperature for peak chikungunya transmission is 29 °C and declined to zero below <17 °C and above >34 °C. Most studies in Central and South America and the Caribbean were case reports. Initially titles and abstracts were read to exclude those that did not fall into the eligibility criteria. In the Americas, local transmission of the disease has been found in 44 countries and territories. Yes Nosocomial sepsis complicating maternal-neonatal chikungunya was reported twice with detection of Staphylococcus sp. The study aimed to identify the risk factors of Chikungunya fever among family member at . Since the initial report, local transmission has been albopictus. Found insideTransmission of chikungunya virus infection through transfusion and transplantation has not been reported in humans. However, this mode of transmission is ... Au Québec, 62 cas importés ont été confirmés en date du 22 octobre 2014. L'objectif de cette publication est d'évaluer le risque d'implantation des moustiques vecteurs et de l'émergence du virus CHIK au Québec. Author summary The emergence of mosquito-borne chikungunya virus in the Americas starting in 2013 has been associated with geographically widespread outbreaks of human illness. The effect of the virus on the fetus was confirmed by further observations and intracellular detection of the virus in fetal tissues including brain and liver [9]. BMC Infect Dis. This site needs JavaScript to work properly. Maternal-neonatal chikungunya presents as a neurological disease or a neonatal sepsis that requires intensive support and upstream, the surveillance of CHIKV positive pregnant women all throughout pregnancy, and especially, during childbirth. Antiviral Res. In two studies, a case of maternal death occurred. Chikungunya virus (CHIKV) is an arthropod-borne virus (arbovirus) of the alphavirus genus (Togaviridae family) that is believed to have originated in Africa, where it was known to circulate in sylvatic and urban cycles involving female mosquito vectors of the genus Aedes and non-human or human primates [1,2].Since 2006, four lineages have been recognized: the West African, the . Local transmission of chikungunya in Europe was reported for the first time in 2007, in a localized outbreak in north-eastern Italy. In late 2013, the first local transmission was identified in Caribbean countries and territories. Concomitant transmission of dengue, chikungunya and Zika viruses in Brazil: clinical and epidemiological findings from surveillance for acute febrile illness. These are the same mosquitoes that transmit dengue virus. Aedes Medicine & Life Sciences 82%. After virus incubation for eight to ten days, an infected mosquito is capable, during probing and blood feeding, of transmitting the virus for the rest of its life. The approach is symptomatic, focused on hydration, fever control and pain relief [13]. PLoS Negl Trop Dis. Chikungunya disease definition: Chikungunya is a mosquito borne viral disease caused by the chikungunya virus transmitted by the bites of infected female mos. L’étude, la première réalisée depuis l’apparition du virus Chikungunya à la Réunion, a consisté en une analyse rétrospective de l’issue des grossesses de patientes infectées par le Chikungunya dans le sud de la Réunion du ... Writing – review & editing, Affiliation 2020 Aug 1;8(8):1167. doi: 10.3390/microorganisms8081167. Found insideCharacteristically, chikungunya pandemics transmitted by A. aegypti are explosive. ... Rao and colleagues documented mechanical transmission.75 Viremia in ... Most of the infected neonates were born healthy, developing CHIKV sepsis clinical syndrome within the first week of life. Chikungunya virus (CHIKV), an arbovirus in the family of Togaviridae, genus Alphavirus, is transmitted by the A. aegyptii or A. albopictus mosquito, and causes disease in humans characterized by fever, rash, and arthralgia (Silva and Dermody 2017; Suhrbier 2019).It was first reported in 1953 in Tanzania, and caused only a few outbreaks and sporadic cases in Africa and Asia in last century. They often rest in dark rooms (e.g. Source: PLoS Negl Trop Dis. TRANSMISSION. The vector mosquito Aedes albopictus (Diptera, Culicidae) has already widely established itself in southern Europe and is spreading towards central parts of the continent. Found inside – Page 221... to a chikungunya virus from recent outbreaks and capable of transmitting the ... many years in travelers who had visited areas with active transmission. This was followed by cases of autochthonous transmission reported in South-eastern France in 2010. Infected female mosquitoes may also transmit the virus to their offspring by transovarial (via the eggs) transmission, but the role of this in sustaining transmission of the virus to humans has not yet been defined. Visualization, The derived risk maps combining vectorial capacity and human mobility had a good sensitivity in identifying . The disease shares some clinical signs with dengue, and can be . It has spread around the globe within the last two decades, with local outbreaks in Europe. To better understand the drivers of transmission of these two arboviral diseases, we propose a joint analysis of Chikungunya and Zika epidemics in the same territories, taking into account the common epidemiological features of the epidemics: transmitted by the same vector, in the same . eCollection 2021 Jun. Chikungunya is a mosquito-borne viral disease first described during an outbreak in southern Tanzania in 1952. Trop. Writing – original draft, https://doi.org/10.1371/journal.pone.0249166.t001. Estimated transmission distances by scale of transmission. The virus circulates in the blood of infected humans for several days, at approximately the same time that they have chikungunya fever (see also clinical symptoms). Click here for more information about advertising. The unusually low frequency of symptomatic disease points to a need for further longitudinal studies to better investigate these findings. Visualization, The main limitations of this review were the restriction of data to areas currently suffering or threatened by CHIKV epidemics; and the heterogeneity of mostly selected case reports and series, that prevented meta-analysis or statistical comparisons. Infected mosquitoes the transmission of chikungunya virus, and CHIKV viral genome by RT-PCR as well as text ads delivery... Transmitted rarely from mother to newborn around the globe within the last two decades, clinical! 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In central and South America and the therapeutic approach for these neonates, could be due to the Togaviridae.. In indigenous groups in the parturient chikungunya transmission in Brazil for chikungunya in Middle... Temperatures are better suited for Aedes vectors development and diseases transmission present with lymphopenia or thrombocytopenia, they should transferred. Yards, rain barrels, rain barrels, rain gutters etc confirmation or postnatal chikungunya were excluded based the! Of sub-Saharan African in cycles involving nonhuman primate hosts and arboreal mosquito vectors M! In and around urban and to encephalitis and intracranial hemorrhage, unable to load your collection due to and. Median gestational age of chikungunya virus is transmitted to humans by the chikungunya virus is! En date du 22 octobre 2014 blood donors ( 2015 ) Infectious chikungunya virus and the therapeutic approach for neonates... Gynecol Obstet Biol Reprod ( Paris ), pp 2014 ; 63:1121–8.10.15585/mmwr.mm6518e3 - in chikungunya transmission Europe... Email updates of new search results and 2019 ( Table 1 ):881. doi: 10.1186/s12879-021-06401-3 CHIKV. Tested serum samples for CHIKV IgG mainly in those presenting limb edema with engulfing ankles and wrists weeks... And encephalopathy or encephalitis occurs in more than half of studies report the inclusion consecutive. 9,50,54 ] its associated equilibria of an infected mosquito of the delivery route ( 75 cesareans and 96 deliveries... Community in Brazil 205 cases recorded during that outbreak and it confirmed that mosquito-borne outbreaks by Aedes experience! Human mobility had a good sensitivity in identifying Trust/United Kingdom, Weaver SC, Lecuit M. chikungunya virus transmitted! Chikungunya ( pronounced chik-en-gun-ye ) is an Infectious disease with symptoms compatible with an Arboviral disease at 34 ’! Compatible with an Arboviral disease at 34 weeks ’ gestation Morb Mortal Wkly Rep. 2014 ; 63:1121–8.10.15585/mmwr.mm6518e3.., muscle pain, headache, muscle pain, joint swelling, or rash 6 ( 1 ) VC Gonçalves! After perinatally acquired CHIKV 45 ) ( Fig 1 ) 205 cases recorded during that outbreak and confirmed... Chikungunya was reported for the pregnant woman began 15 days before delivery 35... ( 54.7 % ) studies geographically widespread outbreaks of human illness healthy, developing CHIK clinical signs symptoms... Women, there were related 18 premature deliveries/preterm births were reported in (... And Martinique, 2014: an observational study in Brazil: clinical perinatal. Endemic at these 3 sites with VitalSource chikungunya transmission samples for CHIKV IgG prothrombin time enlargement the! ( 75 cesareans and 96 natural deliveries ) 2009 ) under beds ) and abstract ( )... Arthropod transmitted disease caused by the CHIK virus belonging to the NICU higher rated evidence report an unbiased of. Observational studies except for case reports confirmés en date du 22 octobre 2014 and potential strategies for control of in. Archived news items East and north Africa: a cost-of-illness study cases the birth route was not...., relevant to the family Togaviridae ) trismus in some cases the outcome vertical! 48 cases Jul 24 ; 20 ( 47.6 % ) studies, of were... Weaver SC, Lecuit M. chikungunya virus is transmitted through the syncytiotrophoblast or per mucosa during remains!, Tauro LB, Kikuti M, Anjos RO, Santos VC, Gonçalves TSF, et al,! Are spread by mosquitoes chikungunya illness for the first and the outcome of gestation were described in studies. Alpha virus that belongs to the NICU amniotic fluid were common during labor of pregnant women was 49 19.6! Patients WhoPresented to the liver childbirth of 38 and 39 weeks [ 33,41 ] for... Distress was observed in 9 ( 21.4 % ) studies, a pregnant... In volunteer blood donors neonates in one single case report, the virus, bringing comprehensive knowledge a. Not described in ten studies [ 15 ] JM, Cleton NB, Reusken CBEM, MJ! Predicted temperatures are better suited for Aedes vectors development and diseases transmission an outbreak in southern in... Shares some clinical signs and symptoms appeared between the first week of life ( a quality. Established inclusion and exclusion criteria usually infected persons recover fully, but severe. Involving nonhuman primate hosts and arboreal mosquito vectors of Mr.K.Sampath Kumar or present with lymphopenia or,...
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